A detailed survey of nutrition and energy expenditure was undertaken to
establish the effects of chronic cold exposure and changing levels of activity
upon the nutritional requirements of m e n living at an antarctic base. This
Alaskan groiond squirrels exhibited a profound leucopenia
during hibernation and hypothermia. The total number of
erythrocytes declined slightly also but the differences could
not be established as statistically significant. The packed
In rats acutely exposed to cold as compared to room temperature,
the toxic responses to parenteral injections of meperidine
hydrochloride, of dextroamphetamine sulfate and of prochlorperazine
ethane sulfonate were invariably greater in cold than at...
Mice singly housed and exposed to 5 C are almost as
responsive as animals at 25° C in carrying out glyconeogenesis
following a single injection of cortisone. An LD50 of endotoxin
lowers liver glycogen about equally in mice housed at each of
paper reports the results of measurements of metabolism
and body temperatures taken during 14 nights of comfortably w a rm
sleep in six male Eskimos from the village of Wainwright on the
arctic coast of Alaska. The mean age of these subjects was...
present brief study was planned to investigate the effect on CIVD of
depth of immersion of the finger in ice water. Pain sensation was also
recorded, since m a n y persons have found this modality to be temporally related
to the vascular reaction...
Rats fed meals of high- and low-carbohydrate diets (2 hours
daily) were either forced to swim at 3 8 - 4 0 C for 1-1/2 hours
daily for 15 days or kept in a 7° C cold room for approximately
4 weeks. On the low-carbohydrate diet, liver glutamic...
Rats prefed for 36 or 48 hours on a synthetic diet containing 10 percent
added glycine show a marked ability to maintain carbohydrate stores following
stresses compared to animals fed the diet without glycine (the "glycine
effect"" The stresses...
The inhibition of tryptophan pyrrolase in vitro by plasma
and certain other native substances was investigated in an
attempt to elucidate mechanisms responsible for the assumed
decrease in activity of this enzyme in vivo during endotoxin
The one-half relaxation time (1/2 RT) for the triceps surae reflex
was studied in four subjects after five-minute runs at 134m/inin
(5 mi/hr) on a treadmill set at 10% grade. This exercise decreased
1/2 R T to 9 0 % of normal. Cooling by immersion...
The quantitative aspects of iodine metabolism have been
evaluated in normal healthy human subjects by means of a tracing
method and long-term iodine balance studies. The behavior
of the specific activities of hormonal iodine in the intra-...
The research project was undertaken to determine what, if any, are the
principal factors in the diet which m a y induce or aggravate cardiovascular
stress during refeeding following starvation. This report describes the first
These studies have excluded the role of silicone and
oxygen bubbles in the genesis of brain and spinal cord
damage. The studies confirm the fact that 60 min of circulatory
standstill is the upper limit of the tolerable ischemia
even at temperatures...
Thirteen series of experiments were conducted to determine
some hemodynamic and metabolic responses of infused L M D
(low molecular weight dextran, 40, 000) in rats. Oxygen consumption,
respiratory quotient, circulating histamine levels,...
When rats are fed a semisynthetic diet containing 1 0 % glycine and then
stressed (cold water swim), the animals maintain liver glycogen at a
much higher level than do animals treated similarly but fed the diet without
the added glycine. During a...